Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | CCR5 | P51681 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448944 | 1.00 | DPP8 (0.34) | DPP8DPP9ALDH1A1MAPTCCR5 | |
| SCHEMBL7452803 | 0.95 | CCR5 (0.34) | DPP8DPP9ALDH1A1CCR5 | |
| SCHEMBL7452809 | 0.95 | CCR5 (0.34) | DPP8DPP9ALDH1A1CCR5 | |
| SCHEMBL7453401 | 0.86 | DPP8 (0.33) | DPP8DPP9ALDH1A1MAPTCCR5 | |
| SCHEMBL7453411 | 0.86 | DPP8 (0.35) | DPP8DPP9ALDH1A1MAPTMEN1 | |
| SCHEMBL7453395 | 0.86 | DPP8 (0.35) | DPP8DPP9ALDH1A1MAPTMEN1 | |
| SCHEMBL7453675 | 0.83 | ALDH1A1 (0.36) | DPP8DPP9ALDH1A1MAPTMEN1 | |
| SCHEMBL7453669 | 0.83 | ALDH1A1 (0.36) | DPP8DPP9ALDH1A1MAPTMEN1 | |
| SCHEMBL7461111 | 0.83 | CCR5 (0.34) | DPP8DPP9ALDH1A1CCR5KDM4E | |
| SCHEMBL7461108 | 0.83 | CCR5 (0.34) | DPP8DPP9ALDH1A1CCR5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882728-B1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO CO (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |