Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.60 |
| ▸ | PLG | P00747 | 2/20 | 0.60 |
| ▸ | PROC | P04070 | 2/20 | 0.60 |
| ▸ | F2 | P00734 | 9/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993791 | 0.88 | F2 (0.63) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8993767 | 0.84 | F2 (0.62) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8993740 | 0.84 | F2 (0.58) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8993790 | 0.83 | F2 (0.66) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8993691 | 0.80 | F2 (0.64) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8993694 | 0.80 | F2 (0.61) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8993724 | 0.79 | F10 (0.73) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8993800 | 0.79 | F10 (0.70) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8993743 | 0.78 | F10 (0.63) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8993711 | 0.78 | F10 (0.54) | F10PLGPROCF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975608-A2 | HALO-ALKOXYCARBONYL PRODRUGS | Genentech, Inc. (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046576-A2 | HALO-ALKOXYCARBONYL PRODRUGS | GENENTECH, INC. (US) | 1998-10-22 | — | — | WO | disclosed |