SCHEMBL8993724

SCHEMBL8993724

COc1ccc2ccc(S(=O)(=O)NC3CCN(C(Cc4ccc(C(=N)N)cc4)C(=O)O)C3=O)cc2c1

nearest known ligand 0.73

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.73
F2 P00734 6/20 0.64
PLG P00747 2/20 0.64
PROC P04070 2/20 0.64
PRSS1 P07477 2/20 0.64
PLAT P00750 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8993800 0.98 F10 (0.70) F10F2PLGPROCPRSS1
SCHEMBL8993684 0.95 F10 (0.69) F10F2PLGPROCPRSS1
SCHEMBL8993746 0.94 F10 (0.66) F10F2PLGPROCPRSS1
SCHEMBL8993743 0.93 F10 (0.63) F10F2PLGPROCPRSS1
SCHEMBL8993681 0.93 F10 (0.69) F10F2PLGPROCPRSS1
SCHEMBL8993808 0.91 F10 (0.68) F10F2PLGPROCPRSS1
SCHEMBL8993718 0.91 F10 (0.67) F10F2PLGPROCPRSS1
SCHEMBL8993791 0.90 F2 (0.63) F10F2PLGPROCPRSS1
SCHEMBL8993695 0.89 F10 (0.59) F10F2PLGPROCPRSS1
SCHEMBL8993813 0.89 F10 (0.65) F10F2PLGPROCPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489583-A FOR TREATING OR PREVENTING THROMBOSIS BASF AKTIENGESELLSCHAFT (DE) 1996-02-06 US disclosed