Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.51 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607568 | 0.92 | PTGER1 (0.53) | PTGER1TLR7TDP1MEN1KMT2A | |
| SCHEMBL7449280 | 0.90 | PTGER1 (0.53) | PTGER1TLR7TDP1MEN1KMT2A | |
| SCHEMBL7450591 | 0.88 | PTGER1 (0.51) | PTGER1TLR7TDP1ALDH1A1LMNA | |
| SCHEMBL7452183 | 0.88 | SMPD1 (0.54) | PTGER1TLR7MEN1KMT2ANR1H4 | |
| SCHEMBL7452683 | 0.85 | PTGER1 (0.48) | PTGER1TLR7TDP1LMNAL3MBTL1 | |
| SCHEMBL7502192 | 0.84 | PTGER1 (0.49) | PTGER1TLR7TDP1KDM4EALDH1A1 | |
| SCHEMBL7443767 | 0.82 | PTGER1 (0.51) | PTGER1TLR7MEN1KMT2AKDM4E | |
| SCHEMBL7447138 | 0.82 | PTGER1 (0.54) | PTGER1TLR7TDP1HDAC6HDAC1 | |
| SCHEMBL6983082 | 0.82 | PTGER1 (0.56) | PTGER1TLR7TDP1KDM4EALDH1A1 | |
| SCHEMBL7498276 | 0.82 | TLR7 (0.54) | PTGER1TLR7SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977743-A1 | PROTEASE INHIBITORS | Smithkline Beecham (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998049152-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |