Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449280 | 0.94 | PTGER1 (0.53) | PTGER1TLR7TDP1MAPTNPY1R | |
| SCHEMBL7607568 | 0.92 | PTGER1 (0.53) | PTGER1TLR7TDP1MAPTNPY1R | |
| SCHEMBL7447783 | 0.89 | PTGER1 (0.49) | PTGER1GALR3TLR7HDAC1HDAC8 | |
| SCHEMBL7449173 | 0.88 | PTGER1 (0.51) | PTGER1TLR7TDP1MAPTATM | |
| SCHEMBL7447935 | 0.88 | PTGER1 (0.44) | PTGER1GALR3TLR7MAPTRAB9A | |
| SCHEMBL7447932 | 0.83 | PTGER1 (0.43) | PTGER1TLR7CHEK1LMNA | |
| SCHEMBL7443767 | 0.82 | PTGER1 (0.51) | PTGER1TLR7MAPTL3MBTL1RAB9A | |
| SCHEMBL7502192 | 0.82 | PTGER1 (0.49) | PTGER1TLR7TDP1MAPTL3MBTL1 | |
| SCHEMBL7447138 | 0.82 | PTGER1 (0.54) | PTGER1TLR7TDP1HDAC1HDAC8 | |
| SCHEMBL6983082 | 0.82 | PTGER1 (0.56) | PTGER1TLR7TDP1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977743-A1 | PROTEASE INHIBITORS | Smithkline Beecham (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998049152-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |