Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11632220 | 0.82 | ROCK1 (0.55) | KDM4EKMT2AMEN1RAB9AMAPT | |
| SCHEMBL9382436 | 0.77 | GAA (0.51) | KDM4EKMT2AMEN1HPGDRAB9A | |
| SCHEMBL8853392 | 0.77 | CASP3 (0.57) | KDM4EKMT2AMEN1HPGDRAB9A | |
| SCHEMBL3422728 | 0.77 | GAA (0.55) | KDM4EKMT2AMEN1HPGDRAB9A | |
| SCHEMBL7351218 | 0.76 | POLB (0.57) | KMT2AMEN1RAB9AMAPTALDH1A1 | |
| SCHEMBL17384015 | 0.75 | MEN1 (0.61) | KDM4EKMT2AMEN1MAPTALDH1A1 | |
| Benzene SCHEMBL29129490 | 0.75 | GAA (0.58) | KDM4EKMT2AMEN1HPGDRAB9A | |
| SCHEMBL418428 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL28317066 | 0.75 | GAA (0.54) | KDM4EKMT2AMEN1HPGDRAB9A | |
| Acetic Acid SCHEMBL10585627 | 0.75 | GAA (0.49) | KDM4EKMT2AMEN1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977743-A1 | PROTEASE INHIBITORS | Smithkline Beecham (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998049152-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |