SCHEMBL8853392

SCHEMBL8853392

O=C(CCl)Nc1cccs1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 2/20 0.57
CASP2 P42575 1/20 0.57
GAA P10253 13/20 0.51
MEN1 O00255 11/20 0.51
KMT2A Q03164 11/20 0.51
MAPT P10636 11/20 0.51
HSD17B10 Q99714 10/20 0.51
ALDH1A1 P00352 6/20 0.51
HTT P42858 5/20 0.51
HPGD P15428 3/20 0.51
KDM4E B2RXH2 2/20 0.51
PKM P14618 2/20 0.51
ALOX15 P16050 8/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
ALOX12 P18054 1/20 0.50
MAPK1 P28482 1/20 0.50
GFER P55789 3/20 0.49
RAB9A P51151 6/20 0.49
LMNA P02545 2/20 0.49
GSK3B P49841 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3422728 0.81 GAA (0.55) GAAMEN1KMT2AMAPTHSD17B10
SCHEMBL9382436 0.81 GAA (0.51) CASP3GAAMEN1KMT2AMAPT
Hydrochloric Acid SCHEMBL28317066 0.79 GAA (0.54) GAAMEN1KMT2AMAPTHSD17B10
SCHEMBL21067510 0.78 GAA (0.49) CASP3GAAMEN1KMT2AMAPT
SCHEMBL6464495 0.78 ADORA2A (0.56) GAAMEN1KMT2AMAPTHSD17B10
SCHEMBL9547640 0.77 GAA (0.72) CASP3GAAMEN1KMT2AMAPT
SCHEMBL28723721 0.77 GAA (0.58) CASP3GAAMEN1KMT2AMAPT
SCHEMBL7449231 0.77 KDM4E (0.60) MEN1KMT2AMAPTHSD17B10ALDH1A1
SCHEMBL27489667 0.77 GAA (0.47) CASP3GAAMEN1KMT2AMAPT
Benzene SCHEMBL29129490 0.75 GAA (0.58) CASP3GAAMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103747675-B Herbicidal compositions comprising chloroacetamides 巴斯夫欧洲公司 2016-06-29 CN disclosed
CN-103747675-A Herbicidal compositions comprising chloroacetamides BASF SE 2014-04-23 CN disclosed
US-5703248-A Process for the selective trihalogenation of ketones useful as intermediates in the synthesis of thiophenes ROMMEL JEFFREY S (US) 1997-12-30 US disclosed
US-5543531-A Thiophen compounds and their preparation SANDOZ LTD. (CH) 1996-08-06 US disclosed
EP-0296463-B1 THIOPHEN COMPOUNDS AND THEIR PREPARATION SANDOZ AG (CH) 1992-06-10 EP disclosed
EP-0210320-B1 PROCESS FOR THE PREPARATION OF N-THIENYL-CHLOROACETAMIDES SANDOZ AG 1989-05-24 EP disclosed
US-4806656-A Preparation of N-thienyl-chloroacetamides and tetrahydro-thien-3-ylidenimines SANDOZ LTD. (CH) 1989-02-21 US disclosed
US-4806656-A Preparation of N-thienyl-chloroacetamides and tetrahydro-thien-3-ylidenimines SANDOZ LTD. (CH) 1989-02-21 US disclosed
WO-1988010261-A1 NOVEL THIOPHEN COMPOUNDS AND THEIR PREPARATION SANDOZ AG (CH) 1988-12-29 WO disclosed
EP-0296463-A2 Thiophen compounds and their preparation SANDOZ AG (CH) 1988-12-28 EP disclosed
US-4666502-A Herbicidal N-thienyl-chloroacetamides SANDOZ LTD. (CH) 1987-05-19 US disclosed
EP-0210320-A1 Process for the preparation of N-thienyl-chloroacetamides SANDOZ AG (CH) 1987-02-04 EP disclosed
EP-0210320-A1 Process for the preparation of N-thienyl-chloroacetamides SANDOZ AG (CH) 1987-02-04 EP disclosed