Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 10/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388132 | 0.88 | KCNH2 (0.40) | HSD17B3MAOBIDO1KDM4EALDH1A1 | |
| SCHEMBL7383110 | 0.75 | KCNH2 (0.38) | HSD17B3MAOBIDO1KDM4EALDH1A1 | |
| SCHEMBL548396 | 0.73 | IDO1 (0.45) | HSD17B3MAOBIDO1KDM4EALDH1A1 | |
| SCHEMBL7495329 | 0.73 | SLC6A4 (0.53) | HSD17B3MAOBIDO1ACHEALPI | |
| SCHEMBL7495322 | 0.73 | SLC6A4 (0.53) | HSD17B3MAOBIDO1ACHEALPI | |
| SCHEMBL7450620 | 0.73 | KDM4E (0.50) | MAOBKDM4EALDH1A1 | |
| SCHEMBL8032293 | 0.72 | MAOB (0.47) | HSD17B3MAOBIDO1KDM4EALDH1A1 | |
| SCHEMBL18347517 | 0.71 | IDO1 (0.51) | HSD17B3MAOBIDO1KDM4EALDH1A1 | |
| SCHEMBL2256874 | 0.71 | KDM4E (0.46) | KDM4EALDH1A1GLAMAOA | |
| SCHEMBL6635463 | 0.69 | IDO1 (0.41) | HSD17B3MAOBIDO1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |