Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026433 | 0.84 | MAOB (0.37) | MAOBSRCMAOAKDM4ECA12 | |
| SCHEMBL6635463 | 0.81 | IDO1 (0.41) | MAOBSRCMAOAKDM4ECA12 | |
| SCHEMBL8015825 | 0.81 | KCNH2 (0.43) | MAOBKDM4EALDH1A1GAAHPGD | |
| SCHEMBL8016102 | 0.79 | MAOB (0.47) | MAOBMAOAALDH1A1ACHE | |
| SCHEMBL11877181 | 0.77 | MAPT (0.44) | MAOBSRCMAOAKDM4ECA12 | |
| SCHEMBL7449274 | 0.72 | HSD17B3 (0.44) | MAOBMAOAKDM4EALDH1A1GLA | |
| SCHEMBL14224119 | 0.69 | CYP3A4 (0.64) | CA12ALDH1A1CA1CA9IDO1 | |
| SCHEMBL28668975 | 0.68 | HSD17B3 (0.73) | MAOBKDM4EALDH1A1GLAGAA | |
| SCHEMBL2000840 | 0.67 | SRC (0.63) | MAOBSRCMAOAKDM4ECA12 | |
| SCHEMBL31683270 | 0.67 | KDM4E (0.48) | MAOBKDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |