Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902556 | 0.80 | MAOA (0.45) | ALDH1A1TDP1KDM4ETSHRGLA | |
| SCHEMBL6282287 | 0.79 | ALOX5AP (0.50) | ALOX5APFEN1ALDH1A1TDP1KDM4E | |
| SCHEMBL5175215 | 0.77 | ALOX5AP (0.44) | ALOX5APFEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3781939 | 0.77 | MAOA (0.42) | ALOX5APFEN1ALDH1A1TDP1KDM4E | |
| SCHEMBL28327988 | 0.76 | PDK2 (0.43) | ALDH1A1TDP1TSHRPDK2SMN1; SMN2 | |
| SCHEMBL3789390 | 0.75 | ALDH1A1 (0.51) | ALDH1A1TDP1KDM4ETSHRGLA | |
| SCHEMBL4250948 | 0.74 | ALDH1A1 (0.41) | ALOX5APFEN1ALDH1A1TDP1KDM4E | |
| SCHEMBL1926441 | 0.73 | TSHR (0.70) | ALDH1A1TDP1TSHRGLAGAA | |
| SCHEMBL3805104 | 0.72 | ADORA2A (0.41) | ALDH1A1TDP1KDM4ETSHRGLA | |
| SCHEMBL9404028 | 0.72 | KDM4E (0.48) | ALOX5APFEN1ALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946528-A2 | OXYGEN OR SULFUR CONTAINING 5-MEMBERED HETEROAROMATICS AS FACTOR Xa INHIBITORS | Du Pont Pharmaceuticals Company (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028282-A2 | OXYGEN OR SULFUR CONTAINING 5-MEMBERED HETEROAROMATICS AS FACTOR Xa INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |