Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21925055 | 0.86 | TSHR (0.50) | TSHRPPARDTP53TDP1 | |
| SCHEMBL7456860 | 0.81 | PPARD (0.41) | TSHRPPARDTP53TDP1 | |
| SCHEMBL31219193 | 0.77 | TSHR (0.41) | TSHRPPARDTP53TDP1 | |
| SCHEMBL14548749 | 0.77 | PPARD (0.45) | TSHRPPARDTP53TDP1 | |
| SCHEMBL15026155 | 0.77 | TSHR (0.41) | TSHRPPARDTP53TDP1 | |
| SCHEMBL31219196 | 0.77 | TSHR (0.41) | TSHRPPARDTP53TDP1 | |
| SCHEMBL5552 | 0.77 | TSHR (0.41) | TSHRPPARDTP53TDP1 | |
| SCHEMBL12617289 | 0.76 | NCF1 (0.41) | TSHRPPARDTP53TDP1 | |
| Hydrochloric Acid SCHEMBL31019801 | 0.76 | TSHR (0.40) | TSHRPPARDTP53TDP1 | |
| SCHEMBL7449671 | 0.72 | TSHR (0.37) | TSHRPPARDTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087888-A1 | PYRAZOLOPYRIMIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | SK CHEMICALS CO., LTD. (KR) | 2001-11-22 | — | — | WO | disclosed |