Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL894500 | 0.84 | TSHR (0.46) | TSHRTP53TDP1MEN1KMT2A | |
| SCHEMBL7456997 | 0.80 | PPARD (0.35) | TSHRTP53TDP1PPARDMMP1 | |
| SCHEMBL575751 | 0.78 | MMP1 (0.42) | TSHRTP53TDP1MEN1KMT2A | |
| SCHEMBL2210415 | 0.75 | TSHR (0.37) | TSHRTP53TDP1MEN1KMT2A | |
| SCHEMBL21655008 | 0.73 | TSHR (0.36) | TSHRTP53TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2207049 | 0.73 | TSHR (0.36) | TSHRTP53TDP1MEN1KMT2A | |
| SCHEMBL7449448 | 0.72 | TSHR (0.41) | TSHRTP53TDP1PPARD | |
| SCHEMBL575255 | 0.71 | MMP1 (0.37) | TSHRTP53TDP1MEN1KMT2A | |
| SCHEMBL7456860 | 0.69 | PPARD (0.41) | TSHRTP53TDP1PPARDMMP1 | |
| SCHEMBL576037 | 0.69 | MMP1 (0.39) | TSHRTP53TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087888-A1 | PYRAZOLOPYRIMIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | SK CHEMICALS CO., LTD. (KR) | 2001-11-22 | — | — | WO | disclosed |