Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 3/20 | 0.55 |
| ▸ | ELANE | P08246 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449565 | 0.86 | ELANE (0.58) | CTRB1ELANELCK | |
| SCHEMBL6640855 | 0.83 | CTRB1 (0.57) | CTRB1ELANEALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL6638394 | 0.82 | CTRB1 (0.56) | CTRB1ELANELCKALDH1A1HPGD | |
| SCHEMBL6499069 | 0.82 | ELANE (0.68) | CTRB1ELANELCKMEN1KMT2A | |
| SCHEMBL6804745 | 0.80 | ELANE (0.40) | CTRB1ELANEALDH1A1HPGDMEN1 | |
| SCHEMBL6638795 | 0.79 | ELANE (0.61) | CTRB1ELANELCKL3MBTL1BRD4 | |
| SCHEMBL6636149 | 0.79 | CTRB1 (0.53) | CTRB1ELANELCKCCNCCDK8 | |
| SCHEMBL7442928 | 0.79 | ELANE (0.52) | CTRB1ELANEMKNK2BRD4CCNC | |
| SCHEMBL6640343 | 0.79 | CTRB1 (0.55) | CTRB1ELANEALDH1A1MEN1KMT2A | |
| SCHEMBL7441628 | 0.77 | ELANE (0.65) | CTRB1ELANELCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037485-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | disclosed |