SCHEMBL7449565

SCHEMBL7449565

Cc1c(NC(=O)OC(C)(C)C)ccc2nc(NC(C)(C)C(=O)N(C)CCN(C)C)oc(=O)c12

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ELANE P08246 7/20 0.58
CTRB1 P17538 5/20 0.58
LCK P06239 1/20 0.35
IRAK4 Q9NWZ3 1/20 0.31
P2RX7 Q99572 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA9 Q16790 1/20 0.30
PSMB8 P28062 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6638795 0.89 ELANE (0.61) ELANECTRB1LCKP2RX7
SCHEMBL6636149 0.88 CTRB1 (0.53) ELANECTRB1LCKP2RX7
SCHEMBL7449580 0.86 CTRB1 (0.55) ELANECTRB1LCK
SCHEMBL6640343 0.86 CTRB1 (0.55) ELANECTRB1
SCHEMBL6634354 0.85 CTRB1 (0.53) ELANECTRB1P2RX7
SCHEMBL7441628 0.85 ELANE (0.65) ELANECTRB1LCK
SCHEMBL6499069 0.85 ELANE (0.68) ELANECTRB1LCKP2RX7CA12
SCHEMBL6641652 0.84 CTRB1 (0.57) ELANECTRB1LCKIRAK4P2RX7
SCHEMBL6638831 0.83 CTRB1 (0.54) ELANECTRB1P2RX7
SCHEMBL6866271 0.81 ELANE (0.66) ELANECTRB1LCKP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996037485-A1 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS G.D. SEARLE & CO. (US) 1996-11-28 WO disclosed