Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LIPC | P11150 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL356821 | 0.80 | ALDH1A1 (0.50) | CFTRALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL7444613 | 0.78 | SMN1; SMN2 (0.43) | CFTRALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL7191668 | 0.77 | PTGER4 (0.49) | CFTRALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL7361203 | 0.77 | KDM4E (0.43) | CFTRALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL7449675 | 0.75 | CFTR (0.46) | CFTRALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL2235637 | 0.72 | CYP1A2 (0.55) | CFTRALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL356011 | 0.72 | ALDH1A1 (0.54) | CFTRALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL27684987 | 0.72 | ALDH1A1 (0.48) | CFTRALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL11874548 | 0.72 | ALDH1A1 (0.52) | CFTRALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL30129591 | 0.72 | NLRP3 (0.44) | CFTRALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196391-A1 | BENZIMIDAZOLONE DERIVATIVES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001005770-A1 | BENZIMIDAZOLONE DERIVATIVES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-01-25 | — | — | WO | disclosed |