Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7656659 | 0.99 | ITGB3 (0.51) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL7455073 | 0.88 | ITGB3 (0.41) | ITGB3ITGA2B | |
| Acetic Acid SCHEMBL7698285 | 0.86 | ITGB3 (0.54) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL9175702 | 0.83 | ITGB3 (0.60) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL7405707 | 0.83 | ITGB3 (0.55) | ITGB3ITGA2B | |
| SCHEMBL7451025 | 0.82 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL7449631 | 0.79 | ITGB3 (0.45) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL7397288 | 0.79 | ITGB3 (0.53) | ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL7447248 | 0.78 | ITGB3 (0.46) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7662941 | 0.78 | ITGB3 (0.52) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098888-A1 | PIPERAZINONE DERIVATIVES AND THEIR USES | LABORATOIRE L. LAFON (FR) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004000-A1 | PIPERAZINONE DERIVATIVES AND THEIR USES | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |