Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.44 |
| ▸ | F10 | P00742 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661051 | 0.86 | ITGB3 (0.44) | ITGB3ITGA2BMEN1KMT2AF2 | |
| SCHEMBL7661045 | 0.86 | ITGB3 (0.44) | ITGB3ITGA2BMEN1KMT2AF2 | |
| SCHEMBL7449846 | 0.86 | ITGB3 (0.52) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7656659 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Acetic Acid SCHEMBL7654858 | 0.83 | ITGB3 (0.40) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Acetic Acid SCHEMBL7656602 | 0.83 | ITGB3 (0.40) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7398279 | 0.82 | ITGB3 (0.62) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Acetic Acid SCHEMBL7664080 | 0.82 | ITGB3 (0.56) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Acetic Acid SCHEMBL7656489 | 0.82 | ITGB3 (0.40) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7653819 | 0.81 | EP300 (0.41) | ITGB3ITGA2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344456-B1 | ANTICOAGULANTS | LABORATOIRE L. LAFON (FR) | 2002-02-05 | — | — | US | disclosed |