Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 17/20 | 0.88 |
| ▸ | MMP2 | P08253 | 16/20 | 0.88 |
| ▸ | MMP3 | P08254 | 13/20 | 0.88 |
| ▸ | MMP1 | P03956 | 9/20 | 0.88 |
| ▸ | MMP9 | P14780 | 3/20 | 0.62 |
| ▸ | MMP8 | P22894 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499228 | 0.93 | MMP2 (1.00) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7507872 | 0.87 | MMP2 (0.88) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7502269 | 0.84 | MMP13 (0.86) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7514849 | 0.83 | MMP13 (0.81) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7512859 | 0.82 | MMP13 (0.60) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7450637 | 0.81 | MMP2 (0.86) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7447269 | 0.80 | MMP2 (1.00) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7899850 | 0.79 | MMP13 (0.79) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7450640 | 0.77 | MMP2 (0.62) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7516814 | 0.77 | MMP13 (1.00) | MMP13MMP2MMP3MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |