Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 10/20 | 0.57 |
| ▸ | CTSL | P07711 | 13/20 | 0.54 |
| ▸ | CTSS | P25774 | 6/20 | 0.54 |
| ▸ | CTSK | P43235 | 6/20 | 0.54 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181749 | 0.86 | CTSB (0.57) | CTSBCTSLCTSSCTSKCTSF | |
| SCHEMBL6184085 | 0.86 | CTSB (0.57) | CTSBCTSLCTSSCTSKCTSF | |
| SCHEMBL7452244 | 0.86 | CTSB (0.61) | CTSBCTSLCTSSCTSKCTSF | |
| SCHEMBL6203497 | 0.84 | CTSB (0.55) | CTSBCTSLCTSSCTSKCTSF | |
| SCHEMBL6182148 | 0.84 | CTSB (0.55) | CTSBCTSLCTSSCTSKF3 | |
| SCHEMBL6186048 | 0.83 | CTSL (0.74) | CTSBCTSLCTSSCTSK | |
| SCHEMBL6181881 | 0.83 | F3 (0.54) | CTSBCTSLCTSSCTSKF3 | |
| SCHEMBL6182433 | 0.83 | CTSB (0.53) | CTSBCTSLCTSSCTSKCTSF | |
| SCHEMBL6182467 | 0.81 | CTSB (0.45) | CTSBCTSLCTSSCTSK | |
| SCHEMBL5924820 | 0.80 | CTSB (0.58) | CTSBCTSLCTSSCTSKCTSF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161415-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055126-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |