Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TACR3 | P29371 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27941122 | 0.86 | KDM4E (0.54) | ACHELMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL1259674 | 0.83 | ACHE (0.59) | ACHELMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL27367367 | 0.83 | ACHE (0.51) | ACHELMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL13243228 | 0.81 | ESRRB (0.59) | ACHELMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL6631411 | 0.81 | ACHE (0.58) | ACHELMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL27914382 | 0.81 | ACHE (0.58) | ACHELMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL4270886 | 0.81 | ACHE (0.58) | ACHELMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL3968020 | 0.81 | ACHE (0.58) | ACHELMNASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL28619856 | 0.80 | ACHE (0.56) | ACHELMNASMN1; SMN2KDM4EPDE10A | |
| Hydrochloric Acid SCHEMBL1260759 | 0.80 | ACHE (0.56) | ACHELMNASMN1; SMN2KDM4EPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002048116-A2 | INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-06-20 | — | — | WO | disclosed |