Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | FPR2 | P25090 | 3/20 | 0.41 |
| ▸ | FPR1 | P21462 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7454721 | 0.98 | ITGB3 (0.54) | ITGB3ITGA2BFPR2FPR1MIF | |
| SCHEMBL7455092 | 0.90 | ITGB3 (0.57) | ITGB3ITGA2BFPR2FPR1MIF | |
| SCHEMBL7449818 | 0.89 | ITGB3 (0.70) | ITGB3ITGA2BFPR2FPR1MIF | |
| SCHEMBL7449975 | 0.88 | ITGB3 (0.53) | ITGB3ITGA2BFPR2FPR1MIF | |
| Hydrochloric Acid SCHEMBL7447965 | 0.88 | ITGB3 (0.69) | ITGB3ITGA2BFPR2FPR1MIF | |
| SCHEMBL7444880 | 0.87 | ITGB3 (0.59) | ITGB3ITGA2BFPR2FPR1KMT2A | |
| SCHEMBL7449994 | 0.86 | ITGB3 (0.62) | ITGB3ITGA2BFPR2FPR1KMT2A | |
| SCHEMBL7446276 | 0.86 | ITGB3 (0.52) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7449230 | 0.85 | ITGB3 (0.59) | ITGB3ITGA2BFPR2FPR1KMT2A | |
| SCHEMBL7449922 | 0.85 | ITGB3 (0.59) | ITGB3ITGA2BFPR2FPR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | claimed |
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | claimed |