Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | FPR2 | P25090 | 11/20 | 0.43 |
| ▸ | FPR1 | P21462 | 9/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413115 | 0.90 | ITGB3 (0.55) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7444880 | 0.89 | ITGB3 (0.59) | ITGB3ITGA2BFPR2FPR1KDM4E | |
| SCHEMBL7455089 | 0.88 | ITGB3 (0.56) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7449818 | 0.88 | ITGB3 (0.70) | ITGB3ITGA2BFPR2FPR1KDM4E | |
| Acetic Acid SCHEMBL7418347 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| Hydrochloric Acid SCHEMBL7447965 | 0.87 | ITGB3 (0.69) | ITGB3ITGA2BFPR2FPR1KDM4E | |
| SCHEMBL8093679 | 0.86 | ITGB3 (0.56) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7445991 | 0.86 | ITGB3 (0.56) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7450172 | 0.86 | ITGB3 (0.51) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7450415 | 0.86 | ITGB3 (0.56) | ITGB3ITGA2BFPR2FPR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | claimed |
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | disclosed |