Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 9/20 | 0.58 |
| ▸ | CTSL | P07711 | 9/20 | 0.53 |
| ▸ | CTSS | P25774 | 5/20 | 0.53 |
| ▸ | CTSK | P43235 | 5/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203497 | 0.89 | CTSB (0.55) | CTSBCTSLCTSSCTSKF3 | |
| SCHEMBL6183809 | 0.88 | CTSB (0.61) | CTSBCTSLCTSSCTSKCA2 | |
| SCHEMBL6182874 | 0.88 | CTSB (0.61) | CTSBCTSLCTSSCTSKCA2 | |
| SCHEMBL6183805 | 0.88 | CTSB (0.61) | CTSBCTSLCTSSCTSKCA2 | |
| SCHEMBL6182791 | 0.88 | CTSB (0.61) | CTSBCTSLCTSSCTSKCA2 | |
| SCHEMBL7452244 | 0.85 | CTSB (0.61) | CTSBCTSLCTSSCTSK | |
| SCHEMBL7511749 | 0.84 | CA2 (0.67) | CTSBCTSLCTSSCTSKCA2 | |
| SCHEMBL6180502 | 0.84 | CTSB (0.56) | CTSBCTSLCTSSCTSKCA2 | |
| SCHEMBL6183292 | 0.83 | CTSB (0.58) | CTSBCTSLCTSSCTSKTAS1R3 | |
| SCHEMBL5925030 | 0.83 | CTSB (0.58) | CTSBCTSLCTSSCTSKCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161415-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055126-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |