Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14862577 | 0.80 | CXCR1 (0.50) | — | |
| SCHEMBL255654 | 0.78 | PARP15 (0.55) | SIGMAR1 | |
| SCHEMBL7450653 | 0.75 | SIGMAR1 (0.51) | SIGMAR1 | |
| SCHEMBL14174984 | 0.75 | HRH3 (0.48) | SIGMAR1 | |
| SCHEMBL4238396 | 0.72 | HRH3 (0.53) | — | |
| SCHEMBL12649216 | 0.71 | TEAD1 (0.58) | SIGMAR1 | |
| SCHEMBL16299517 | 0.71 | MAOA (0.53) | — | |
| SCHEMBL30932889 | 0.70 | PARP15 (0.51) | — | |
| SCHEMBL14863368 | 0.70 | TDP1 (0.68) | — | |
| SCHEMBL25975202 | 0.70 | APP (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020928-A1 | PIPERIDINE-BASED SIGMA RECEPTOR LIGANDS | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) | 1996-07-11 | — | — | WO | disclosed |