⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435324 | 0.92 | — | — | |
| SCHEMBL7431565 | 0.90 | CRBN (0.39) | — | |
| SCHEMBL7430101 | 0.90 | — | — | |
| SCHEMBL7432250 | 0.90 | CRBN (0.39) | — | |
| SCHEMBL75552 | 0.82 | — | — | |
| SCHEMBL522543 | 0.80 | CRBN (0.40) | — | |
| SCHEMBL1646396 | 0.74 | — | — | |
| SCHEMBL828805 | 0.68 | — | — | |
| SCHEMBL9579603 | 0.67 | — | — | |
| SCHEMBL896392 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997495-B1 | 2-phenoxy- and 2-phenylsulfanyl-benzenesulfonamide derivatives with CCR3 antagonistic activity for the treatment of asthma and other inflammatory or immunological disorders | AXIKIN PHARMACEUTICALS INC (US) | 2013-01-02 | — | — | EP | claimed |
| EP-2229374-A1 | AMIDO-THIOPHENE COMPOUNDS AND THEIR USE AS 11-BETA-HSD1 INHIBITORS | THE UNIVERSITY OF EDINBURGH (GB) | 2010-09-22 | — | — | EP | claimed |
| US-20090181966-A1 | PGD2 receptor antagonists for the treatment of inflammatory diseases | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-07-16 | — | — | US | claimed |
| WO-2009074789-A1 | AMIDO-THIOPHENE COMPOUNDS AND THEIR USE AS 11-BETA-HSD1 INHIBITORS | THE UNIVERSITY OF EDINBURGH (GB) | 2009-06-18 | — | — | WO | claimed |
| EP-1608374-B9 | 2-PHENOXY- AND 2-PHENYLSULFOMAMIDE DERIVATIVES WITH CCR3 ANTAGONISTIC ACTIVITY FOR THE TREATMENT OF ASTHMA AND OTHER INFLAMMATORY OR IMMUNOLOGICAL DISORDERS | ACTIMIS PHARMACEUTICALS INC (US) | 2009-04-08 | — | — | EP | claimed |
| EP-1997495-A1 | 2-phenoxy- and 2-phenylsulfanyl-benzenesulfonamide derivatives with ccr3 antagonistic activity for the treatment of asthma and other inflammatory or immunological disorders | Actimis Pharmaceuticals, Inc., (US) | 2008-12-03 | — | — | EP | claimed |
| EP-1991215-A1 | USE OF INHIBITORS OF SCAVENGER RECEPTOR CLASS PROTEINS FOR THE TREATMENT OF INFECTIOUS DISEASES | Cenix Bioscience GmbH (DE) | 2008-11-19 | — | — | EP | claimed |
| EP-1608374-B1 | 2-PHENOXY- AND 2-PHENYLSULFOMAMIDE DERIVATIVES WITH CCR3 ANTAGONISTIC ACTIVITY FOR THE TREATMENT OF ASTHMA AND OTHER INFLAMMATORY OR IMMUNOLOGICAL DISORDERS | ACTIMIS PHARMACEUTICALS INC (US) | 2008-11-05 | — | — | EP | claimed |
| EP-1680420-A4 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2008-09-24 | — | — | EP | claimed |
| WO-2007101710-A1 | USE OF INHIBITORS OF SCAVENGER RECEPTOR CLASS PROTEINS FOR THE TREATMENT OF INFECTIOUS DISEASES | CENIX BIOSCIENCE GMBH (DE) | 2007-09-13 | — | — | WO | claimed |
| EP-1368311-A1 | DELTA1 -PYRROLINES USED IN PEST CONTROL | Bayer CropScience AG (DE) | 2003-12-10 | — | — | EP | claimed |
| WO-2003067986-A1 | Δ1 PYRROLINES AND THE USE THEREOF IN PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2003-08-21 | — | — | WO | claimed |
| WO-2002064561-A1 | $G(D)1-PYRROLINES USED IN PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2002-08-22 | — | — | WO | claimed |
| US-6355615-B1 | CYCLIC POLYAMIDEESTER COPOLYMERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-12 | — | — | US | claimed |
| EP-0986549-A1 | DESOXYCYCLODEPSIPEPTIDES AND THEIR USE FOR COMBATTING ENDOPARASITES | Bayer Aktiengesellschaft (DE) | 2000-03-22 | — | — | EP | claimed |
| WO-1998055469-A1 | DESOXYCYCLODEPSIPEPTIDES AND THEIR USE FOR COMBATTING ENDOPARASITES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-10 | — | — | WO | claimed |
| EP-0406119-B1 | New peptide derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1994-01-19 | — | — | EP | claimed |
| US-5098888-A | Cholinergic agents and antispasmodic agents | ADIR ET COMPAGNIE (FR) | 1992-03-24 | — | — | US | claimed |
| EP-0217688-B1 | PEPTIDE DERIVATIVES WITH A LACTONIC OR CYCLOAMIDIC STRUCTURE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1990-09-26 | — | — | EP | claimed |
| US-4725581-A | NERVOUS SYSTEM DISORDERS, COGNITION ACTIVATORS | ADIR ET COMPAGNIE (FR) | 1988-02-16 | — | — | US | claimed |