SCHEMBL522543

SCHEMBL522543

O=C1CC[CH]NC(=O)CCC1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.40
TRIM24 O15164 2/20 0.39
TRIM33 Q9UPN9 2/20 0.39
ALDH1A1 P00352 1/20 0.38
OR51E2 Q9H255 1/20 0.32
MAPT P10636 1/20 0.31
FKBP5 Q13451 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL745074 0.80
SCHEMBL75552 0.80
SCHEMBL7435324 0.78
SCHEMBL7432250 0.76 CRBN (0.39) CRBNTRIM24TRIM33ALDH1A1OR51E2
SCHEMBL7430101 0.76
SCHEMBL7431565 0.76 CRBN (0.39) CRBNTRIM24TRIM33ALDH1A1OR51E2
SCHEMBL1566729 0.67 TRIM24 (0.82) CRBNTRIM24TRIM33ALDH1A1OR51E2
SCHEMBL27625504 0.67 TRIM24 (0.82) CRBNTRIM24TRIM33ALDH1A1OR51E2
SCHEMBL3393321 0.65 TRIM24 (0.47) TRIM24TRIM33ALDH1A1MAPT
SCHEMBL3697467 0.65 TRIM24 (0.47) TRIM24TRIM33ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140023584-A1 CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING AND PHOTOACOUSTIC IMAGING METHOD USING THE SAME CANON KK (JP) 2014-01-23 US disclosed
EP-2471556-A1 CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING AND PHOTOACOUSTIC IMAGING METHOD UTILIZING SAME Canon Kabushiki Kaisha (JP) 2012-07-04 EP disclosed
US-20120027679-A1 CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING AND PHOTOACOUSTIC IMAGING METHOD USING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-02-02 US disclosed
US-20110117023-A1 CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING AND PHOTOACOUSTIC IMAGING METHOD USING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140023584-A1 CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING AND PHOTOACOUSTIC IMAGING METHOD USING THE SAME L1CAM, TFRC, MPEG1 CRBN 3386/4885TRIM24 2356/4885TRIM33 4689/4885
US-20120027679-A1 CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING AND PHOTOACOUSTIC IMAGING METHOD USING THE SAME L1CAM, TFRC, MPEG1 CRBN 3470/4885TRIM24 2318/4885TRIM33 4710/4885
US-20110117023-A1 CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING AND PHOTOACOUSTIC IMAGING METHOD USING THE SAME L1CAM, TFRC, MPEG1 CRBN 3386/4885TRIM24 2356/4885TRIM33 4689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.