Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441390 | 0.91 | MEN1 (0.46) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7439734 | 0.88 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7440116 | 0.88 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7444296 | 0.88 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7467594 | 0.88 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7465083 | 0.85 | MEN1 (0.43) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7452048 | 0.85 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7500017 | 0.85 | ITGB3 (0.48) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7499673 | 0.85 | ITGB3 (0.48) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7501423 | 0.85 | ITGB3 (0.48) | KMT2AMEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| WO-1996029309-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-26 | — | — | WO | disclosed |