Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6720181 | 0.89 | MEN1 (0.85) | MEN1KMT2APOLBPKMAPEX1 | |
| SCHEMBL7445907 | 0.89 | MEN1 (0.65) | MEN1KMT2AGAARXFP1POLB | |
| SCHEMBL7445967 | 0.86 | MEN1 (0.64) | MEN1KMT2AGAARXFP1CASP6 | |
| SCHEMBL7458365 | 0.86 | MEN1 (0.64) | MEN1KMT2AGAARXFP1PKM | |
| SCHEMBL7452313 | 0.86 | MEN1 (0.64) | MEN1KMT2AGAARXFP1PKM | |
| SCHEMBL7450555 | 0.86 | MEN1 (1.00) | MEN1KMT2APOLBPKMAPEX1 | |
| SCHEMBL7450127 | 0.86 | MEN1 (0.80) | MEN1KMT2APOLBMIFPKM | |
| SCHEMBL13870858 | 0.86 | MEN1 (0.82) | MEN1KMT2APOLBPKMAPEX1 | |
| SCHEMBL7454156 | 0.86 | MEN1 (0.72) | MEN1KMT2APOLB | |
| SCHEMBL6722381 | 0.84 | MEN1 (0.83) | MEN1KMT2APOLBPKMAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | claimed |
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |