Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.54 |
| ▸ | ACLY | P53396 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453398 | 0.90 | RXFP1 (0.54) | MEN1KMT2AGAARXFP1MCL1 | |
| SCHEMBL7458365 | 0.89 | MEN1 (0.64) | MEN1KMT2AGAATAS2R14RXFP1 | |
| SCHEMBL7452313 | 0.86 | MEN1 (0.64) | MEN1KMT2AGAARXFP1ACLY | |
| SCHEMBL7450804 | 0.86 | MEN1 (0.76) | MEN1KMT2AGAARXFP1PKM | |
| SCHEMBL7457668 | 0.83 | MEN1 (0.70) | MEN1KMT2AGAAPPARGPPARD | |
| SCHEMBL6720181 | 0.79 | MEN1 (0.85) | MEN1KMT2APKMAPEX1TP53 | |
| SCHEMBL7450555 | 0.79 | MEN1 (1.00) | MEN1KMT2APKMAPEX1TP53 | |
| SCHEMBL13870867 | 0.78 | CASP3 (0.74) | MEN1KMT2AACLYPPARGPPARD | |
| SCHEMBL7454060 | 0.78 | MEN1 (0.60) | MEN1KMT2AGAATAS2R14RXFP1 | |
| SCHEMBL7445978 | 0.77 | APEX1 (0.58) | MEN1KMT2AGAARXFP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | claimed |
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |