Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.50 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548117 | 0.92 | MEN1 (0.58) | MEN1KMT2AHPGDMAPK10RXFP1 | |
| SCHEMBL7450804 | 0.89 | MEN1 (0.76) | MEN1KMT2ARXFP1GAAPOLB | |
| SCHEMBL7449365 | 0.89 | MEN1 (0.64) | MEN1KMT2ARXFP1POLB | |
| SCHEMBL7449268 | 0.87 | MEN1 (0.68) | MEN1KMT2AHPGDMAPK10CYP2D6 | |
| SCHEMBL7454553 | 0.87 | MEN1 (0.79) | MEN1KMT2AHPGDMAPK10CYP2D6 | |
| SCHEMBL7453398 | 0.87 | RXFP1 (0.54) | MEN1KMT2AHPGDMAPK10RXFP1 | |
| SCHEMBL7452624 | 0.87 | RXFP1 (0.54) | MEN1KMT2AHPGDMAPK10RXFP1 | |
| SCHEMBL7454156 | 0.83 | MEN1 (0.72) | MEN1KMT2APOLB | |
| SCHEMBL7450408 | 0.82 | MEN1 (0.62) | MEN1KMT2AHPGDMAPK10GAA | |
| SCHEMBL7452639 | 0.82 | RXFP1 (0.55) | HPGDMAPK10RXFP1GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |