Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 11/20 | 0.57 |
| ▸ | CTSL | P07711 | 12/20 | 0.52 |
| ▸ | CTSS | P25774 | 7/20 | 0.52 |
| ▸ | CTSK | P43235 | 7/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507894 | 0.90 | CTSB (0.46) | CTSBCTSLCTSSCTSKCNR2 | |
| SCHEMBL7452244 | 0.89 | CTSB (0.61) | CTSBCTSLCTSSCTSKCTSF | |
| SCHEMBL6182114 | 0.85 | CTSB (0.58) | CTSBCTSLCTSSCTSKCTSF | |
| SCHEMBL6183809 | 0.84 | CTSB (0.61) | CTSBCTSLCTSSCTSKCTSF | |
| SCHEMBL6183805 | 0.84 | CTSB (0.61) | CTSBCTSLCTSSCTSKCTSF | |
| SCHEMBL6182791 | 0.84 | CTSB (0.61) | CTSBCTSLCTSSCTSKCTSF | |
| SCHEMBL6182874 | 0.84 | CTSB (0.61) | CTSBCTSLCTSSCTSKCTSF | |
| SCHEMBL6180502 | 0.83 | CTSB (0.56) | CTSBCTSLCTSSCTSKCTSF | |
| SCHEMBL6181880 | 0.83 | CTSB (0.56) | CTSBCTSLCTSSCTSKCTSF | |
| SCHEMBL7450448 | 0.82 | CTSB (0.58) | CTSBCTSLCTSSCTSKTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161415-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055126-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |