Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283100 | 0.79 | SRR (0.50) | CHRM1EPHX1CYP1A2SRRSLC1A3 | |
| SCHEMBL28878522 | 0.79 | ATM (0.50) | CTRB1ALDH1A1MAPT | |
| SCHEMBL29112710 | 0.79 | CYP1A2 (0.44) | CHRM1CYP1A2SRRSLC1A3SLC1A2 | |
| SCHEMBL27987428 | 0.79 | CYP1A2 (0.44) | CHRM1EPHX1CYP1A2SRRSLC1A3 | |
| SCHEMBL7398535 | 0.79 | CRHBP (0.48) | CRHBPCRHR2CHRM1EPHX1KIF11 | |
| SCHEMBL5151597 | 0.79 | ATM (0.50) | CTRB1ALDH1A1MAPT | |
| SCHEMBL7902214 | 0.78 | PPARG (0.41) | CHRM1EPHX1CYP1A2SRRSLC1A3 | |
| SCHEMBL11512005 | 0.78 | ALPI (0.58) | CRHBPCRHR2EPHX1KIF11SRR | |
| SCHEMBL29127421 | 0.78 | CYP1A2 (0.43) | CHRM1CYP1A2SRRSLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL28015582 | 0.78 | ATM (0.49) | CTRB1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950046-A1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | SYNPHAR LABORATORIES INC. (CA) | 1999-10-20 | — | — | EP | disclosed |
| WO-1998012176-A1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | SYNPHAR LABORATORIES INC. (US) | 1998-03-26 | — | — | WO | disclosed |