Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 13/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 12/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 12/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 12/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.38 |
| ▸ | FEN1 | P39748 | 5/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | PLG | P00747 | 2/20 | 0.37 |
| ▸ | PLAT | P00750 | 2/20 | 0.37 |
| ▸ | F7 | P08709 | 2/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357764 | 0.96 | MMP3 (0.42) | MMP3F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7443741 | 0.89 | F2 (0.46) | MMP3F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7434543 | 0.85 | F2 (0.48) | MMP3F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7363801 | 0.84 | MMP3 (0.43) | MMP3F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7365378 | 0.82 | LTB4R (0.38) | — | |
| SCHEMBL7360137 | 0.81 | CA1 (0.36) | — | |
| SCHEMBL7459611 | 0.80 | MMP3 (0.44) | MMP3F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7365875 | 0.80 | CA1 (0.35) | — | |
| SCHEMBL7361085 | 0.75 | PPARG (0.36) | — | |
| SCHEMBL7454504 | 0.74 | ALOX5AP (0.38) | MMP3ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-B1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2002-11-20 | — | — | EP | claimed |
| EP-0892780-B1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2002-11-20 | — | — | EP | disclosed |