Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010300 | 0.89 | HDAC1 (0.66) | ALDH1A1HDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL20597404 | 0.88 | HDAC2 (0.73) | ALDH1A1HDAC2HDAC8HDAC6KDM4E | |
| SCHEMBL28234466 | 0.87 | HDAC1 (0.65) | ALDH1A1HDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL27729715 | 0.85 | ALDH1A1 (0.63) | ALDH1A1HDAC2HDAC8HDAC6KDM4E | |
| SCHEMBL14507607 | 0.85 | HDAC2 (0.59) | ALDH1A1HDAC2HDAC8HDAC6KDM4E | |
| SCHEMBL30572280 | 0.83 | HDAC2 (0.61) | ALDH1A1HDAC2HDAC8HDAC6KDM4E | |
| SCHEMBL3512351 | 0.81 | HDAC2 (0.63) | ALDH1A1HDAC2HDAC8HDAC6KDM4E | |
| SCHEMBL5430589 | 0.81 | HDAC2 (0.63) | ALDH1A1HDAC2HDAC8HDAC6KDM4E | |
| SCHEMBL8013439 | 0.80 | MEN1 (0.61) | ALDH1A1HDAC8HDAC6KDM4EHPGD | |
| SCHEMBL353132 | 0.80 | HDAC2 (0.68) | ALDH1A1HDAC2HDAC8HDAC6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170058002-A1 | GAMMA-AAPEPTIDES WITH POTENT AND BROAD-SPECTRUM ANTIMICROBIAL ACTIVITY | UNIVERSITY OF SOUTH FLORIDA (US) | 2017-03-02 | — | — | US | disclosed |
| CN-105272888-A | Bis-arylalkenylalkyl acid compound, and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2016-01-27 | — | — | CN | disclosed |
| CN-1145609-C | Piperazine compounds and medical use thereof | ������ҩ��ʽ���� | 2004-04-14 | — | — | CN | disclosed |
| EP-1129108-A4 | CASPASES AND APOPTOSIS | SMITHKLINE BEECHAM CORP (US) | 2002-01-09 | — | — | EP | disclosed |
| EP-1129108-A1 | CASPASES AND APOPTOSIS | SmithKline Beecham Corporation (US) | 2001-09-05 | — | — | EP | disclosed |
| CN-1281438-A | Piperazine compounds and their use as pharmaceuticals | EFUKU CO LTD (JP) | 2001-01-24 | — | — | CN | disclosed |
| WO-2000020440-A1 | CASPASES AND APOPTOSIS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170058002-A1 | GAMMA-AAPEPTIDES WITH POTENT AND BROAD-SPECTRUM ANTIMICROBIAL ACTIVITY | ANPEP, DNPEP, ENPEP | ALDH1A1 2713/4885HDAC2 4234/4885HDAC8 3953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.