Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454754 | 0.90 | ALDH1A1 (0.41) | ITGB3ITGA2BALDH1A1KMT2AMEN1 | |
| SCHEMBL7449898 | 0.88 | ALDH1A1 (0.40) | ITGB3ITGA2BALDH1A1KMT2AMEN1 | |
| Acetic Acid SCHEMBL7662510 | 0.88 | F2 (0.47) | ITGB3ITGA2BALDH1A1KMT2AMEN1 | |
| SCHEMBL7448038 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL7449631 | 0.85 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL7447248 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL7658921 | 0.80 | ALDH1A1 (0.39) | ITGB3ITGA2BALDH1A1KMT2AMEN1 | |
| SCHEMBL7658927 | 0.80 | ALDH1A1 (0.39) | ITGB3ITGA2BALDH1A1KMT2AMEN1 | |
| SCHEMBL7455137 | 0.79 | ITGB3 (0.43) | ITGB3ITGA2BF10 | |
| SCHEMBL7660271 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098888-A1 | PIPERAZINONE DERIVATIVES AND THEIR USES | LABORATOIRE L. LAFON (FR) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004000-A1 | PIPERAZINONE DERIVATIVES AND THEIR USES | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |