Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449341 | 0.88 | CTSK (0.34) | CTSKCTSLCTSSCPB2 | |
| SCHEMBL7451263 | 0.84 | CTSK (0.35) | CTSKCTSLCTSS | |
| SCHEMBL7442268 | 0.76 | CTSK (0.46) | CTSKCTSLCTSS | |
| SCHEMBL7455803 | 0.72 | CTSK (0.37) | CTSKCTSLCTSSCCR2CPB2 | |
| SCHEMBL7523273 | 0.72 | CTSK (0.47) | CTSKCTSLCTSS | |
| SCHEMBL5099617 | 0.72 | CTSK (0.42) | CTSKCTSLCTSS | |
| SCHEMBL5105797 | 0.72 | CTSK (0.38) | CTSKCTSLCTSSCCR2 | |
| SCHEMBL7427606 | 0.71 | ALDH1A1 (0.41) | CTSKCTSLCTSS | |
| SCHEMBL5099529 | 0.71 | CTSK (0.37) | CTSKCTSLCTSS | |
| SCHEMBL7451271 | 0.68 | CTSK (0.38) | CTSKCTSLCTSSCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153022-A4 | PROTHEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-1153022-A1 | PROTHEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000049011-A1 | PROTHEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-08-24 | — | — | WO | disclosed |