Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3191297 | 0.85 | MEN1 (0.45) | MAOATSHRMAPTNPC1ABCB1 | |
| SCHEMBL29349908 | 0.85 | MEN1 (0.45) | MAOATSHRMAPTNPC1ABCB1 | |
| SCHEMBL6344640 | 0.73 | AKR1C3 (0.47) | MAPTNPC1MEN1BLMKMT2A | |
| SCHEMBL7076064 | 0.73 | AKR1B1 (0.52) | AKR1B1MAPTCYP2C19CASP3SENP7 | |
| SCHEMBL9467855 | 0.72 | MAOA (0.46) | MAOATSHRMAPTNPC1ABCB1 | |
| Isocoumarin SCHEMBL28729011 | 0.72 | AKR1B1 (0.52) | AKR1B1TSHRMAPTCYP3A4CYP2C9 | |
| SCHEMBL6945650 | 0.67 | MEN1 (0.48) | MAOATSHRMAPTNPC1ABCB1 | |
| SCHEMBL29769302 | 0.66 | MEN1 (0.42) | MAOATSHRMAPTNPC1ABCB1 | |
| SCHEMBL3398957 | 0.66 | MEN1 (0.42) | MAOATSHRMAPTNPC1ABCB1 | |
| SCHEMBL5079030 | 0.65 | ANTXR2 (0.71) | MAOAMAPTCYP3A4ABCG2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017600-A1 | METHODS AND COMPOSITIONS FOR MODULATING ANGIOGENESIS AND PERICYTE COMPOSITION | ACCELERON PHARMA INC. (US) | 2022-01-20 | — | — | US | disclosed |
| US-20210388104-A1 | METHODS AND COMPOSITIONS FOR MODULATING ANGIOGENESIS AND PERICYTE COMPOSITION | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) | 2021-12-16 | — | — | US | disclosed |
| US-10772885-B2 | Composition for treating ocular diseases and methods of usage and making | REYOUNG (SUZHOU) BIOLOGY SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2020-09-15 | — | — | US | disclosed |
| US-10744202-B2 | Sustained release eye drop formulations | RAMSCOR, INC. (US) | 2020-08-18 | — | — | US | disclosed |
| CN-111518218-A | ALK1 receptor and ligand antagonists and uses thereof | 阿塞勒隆制药公司 | 2020-08-11 | — | — | CN | disclosed |
| US-20190224194-A1 | COMPOSITION FOR TREATING OCULAR DISEASES AND METHODS OF USAGE AND MAKING | REYOUNG (SUZHOU) BIOLOGY SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2019-07-25 | — | — | US | disclosed |
| US-10235756-B2 | Vascular analysis methods and apparatus | BIO-TREE SYSTEMS, INC. (US) | 2019-03-19 | — | — | US | disclosed |
| US-20190048063-A1 | METHODS AND COMPOSITIONS FOR MODULATING ANGIOGENESIS AND PERICYTE COMPOSITION | ACCELERON PHARMA INC. (US) | 2019-02-14 | — | — | US | disclosed |
| EP-3398966-A1 | METHODS AND COMPOSITIONS FOR MODULATING ANGIOGENESIS AND PERICYTE COMPOSITION | Acceleron Pharma, Inc. (US) | 2018-11-07 | — | — | EP | disclosed |
| US-20180289810-A1 | SUSTAINED RELEASE EYE DROP FORMULATIONS | RAMSCOR, INC. (US) | 2018-10-11 | — | — | US | disclosed |
| US-20090136445-A1 | SUSTAINED RELEASE EYE DROP FORMULATIONS | RAMSCOR, INC. | 2009-05-28 | — | — | US | disclosed |
| US-20090035308-A1 | Methods for using and identifying modulators of Delta-like 4 | VASGENE THERAPEUTICS, INC. (US) | 2009-02-05 | — | — | US | disclosed |
| US-20080175844-A1 | ALK1 receptor and ligand antagonist and uses thereof | ACCELERON PHARMA, INC. (US) | 2008-07-24 | — | — | US | disclosed |
| WO-2008079326-A2 | METHODS FOR USING AND IDENTIFYING MODULATORS OF DELTA-LIKE 4 | VASGENE THERAPEUTICS, INC. (US) | 2008-07-03 | — | — | WO | disclosed |
| EP-1928486-A2 | METHODS FOR USING AND IDENTIFYING MODULATORS OF DELTA-LIKE 4 | Vasgene Therapeutics, Inc. (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2008057461-A2 | ALK1 RECEPTOR AND LIGAND ANTAGONISTS AND USES THEREOF | ACCELERON PHARMA, INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| US-20080038316-A1 | Conveniently implantable sustained release drug compositions | RAMSCOR, INC. | 2008-02-14 | — | — | US | disclosed |
| US-20070213266-A1 | Methods for using and identifying modulators of Delta-like 4 | VASGENE THERAPEUTICS, INC. (US) | 2007-09-13 | — | — | US | disclosed |
| WO-2007059300-A2 | ANTI-ALK ANTAGONIST AND AGONIST ANTIBODIES AND USES THEREOF | MEDIMMUNE, INC. (US) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007028110-A2 | METHODS FOR USING AND IDENTIFYING MODULATORS OF DELTA-LIKE 4 | VASGENE THERAPEUTICS, INC. (US) | 2007-03-08 | — | — | WO | disclosed |