Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.64 |
| ▸ | BCHE | P06276 | 5/20 | 0.64 |
| ▸ | CNR2 | P34972 | 4/20 | 0.64 |
| ▸ | ACHE | P22303 | 2/20 | 0.64 |
| ▸ | LTA4H | P09960 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.59 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.59 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.59 |
| ▸ | GCGR | P47871 | 1/20 | 0.59 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 7/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452408 | 0.96 | ESR1 (0.64) | CNR1BCHECNR2ACHELTA4H | |
| SCHEMBL11734690 | 0.96 | LTA4H (0.63) | CNR1BCHECNR2ACHELTA4H | |
| SCHEMBL7447390 | 0.95 | L3MBTL1 (0.69) | CNR1BCHECNR2ACHELTA4H | |
| SCHEMBL7946033 | 0.95 | ESR1 (0.65) | CNR1BCHECNR2ACHELTA4H | |
| SCHEMBL11730136 | 0.94 | L3MBTL1 (0.68) | CNR1BCHECNR2ACHELTA4H | |
| Hydrochloric Acid SCHEMBL6749954 | 0.94 | ESR1 (0.66) | CNR1BCHECNR2ACHELTA4H | |
| Hydrochloric Acid SCHEMBL6748794 | 0.93 | L3MBTL1 (0.67) | CNR1BCHECNR2ACHEL3MBTL1 | |
| SCHEMBL11728245 | 0.90 | BCHE (0.57) | CNR1BCHECNR2ACHELTA4H | |
| SCHEMBL8591606 | 0.86 | ESR1 (0.70) | CNR1ACHEESR1ESR2 | |
| SCHEMBL7946146 | 0.85 | ESR1 (0.67) | CNR1ACHELTA4HESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265575-B1 | THROMBIN INHIBITORS | ELI LILLY AND COMPANY | 2001-07-24 | — | — | US | disclosed |
| US-6251921-B1 | ADMINISTERING THROMBIN INHIBITING DIAMINE COMPOUND TO MAMMAL | ELI LILLY AND COMPANY | 2001-06-26 | — | — | US | disclosed |
| US-6025382-A | Antithrombotic diamines | ELI LILLY AND COMPANY (US) | 2000-02-15 | — | — | US | disclosed |
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |