Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 19/20 | 0.86 |
| ▸ | MMP2 | P08253 | 19/20 | 0.86 |
| ▸ | MMP3 | P08254 | 14/20 | 0.86 |
| ▸ | MMP1 | P03956 | 8/20 | 0.86 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449622 | 0.92 | MMP13 (1.00) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL4327772 | 0.79 | MMP13 (1.00) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7502924 | 0.79 | MMP13 (1.00) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7511957 | 0.78 | MMP2 (0.60) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7451546 | 0.78 | MMP2 (0.85) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7502269 | 0.77 | MMP13 (0.86) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7595435 | 0.77 | MMP13 (0.87) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7513667 | 0.74 | MMP13 (0.88) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL22787772 | 0.74 | MMP2 (0.55) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7508942 | 0.74 | MMP13 (0.80) | MMP13MMP2MMP3MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |