Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 8/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262629 | 0.81 | HTT (0.39) | HTTECE1KMT2AACHEEPHX2 | |
| SCHEMBL7446391 | 0.80 | GAA (0.42) | KMT2AACHEGAA | |
| SCHEMBL14762450 | 0.78 | ACHE (0.38) | KMT2AACHEMEN1GAA | |
| SCHEMBL7255174 | 0.78 | HDAC3 (0.46) | HTTECE1KMT2AACHEEPHX2 | |
| SCHEMBL13073328 | 0.77 | ACHE (0.66) | ACHE | |
| SCHEMBL12390787 | 0.77 | ACHE (0.46) | KMT2AACHEMEN1GAA | |
| Hydrochloric Acid SCHEMBL27336202 | 0.76 | HDAC3 (0.45) | HTTECE1KMT2AACHEEPHX2 | |
| SCHEMBL156911 | 0.76 | GAA (0.58) | HTTECE1KMT2ANPSR1MEN1 | |
| SCHEMBL18869307 | 0.76 | TDP1 (0.61) | ACHE | |
| SCHEMBL3264718 | 0.76 | ACHE (0.44) | KMT2AACHEMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124824-A1 | CHROMENONE AND CHROMANONE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GmbH (DE) | 2001-08-22 | — | — | EP | claimed |
| WO-2000026212-A1 | CHROMENONE AND CHROMANONE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GMBH (DE) | 2000-05-11 | — | — | WO | claimed |