Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134492 | 0.79 | PDPK1 (0.44) | NUDT1 | |
| SCHEMBL7453052 | 0.72 | CCNA2 (0.36) | CDK2NUDT1 | |
| SCHEMBL135690 | 0.64 | CDK2 (1.00) | CDK2 | |
| SCHEMBL534997 | 0.63 | PNP (0.59) | — | |
| SCHEMBL140621 | 0.60 | ALDH1A1 (0.50) | — | |
| SCHEMBL7456301 | 0.58 | — | — | |
| SCHEMBL11013210 | 0.56 | — | — | |
| SCHEMBL19313320 | 0.51 | TLR8 (0.44) | CDK2NUDT1 | |
| SCHEMBL18675780 | 0.51 | ALDH1A1 (0.40) | CDK2NUDT1 | |
| SCHEMBL22207103 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916674-B1 | Purine derivatives having cyclopropane ring | SUMIKA FINE CHEMICALS CO LTD (JP) | 2002-05-08 | — | — | EP | disclosed |
| US-6342603-B1 | PREPARING CYCLOPROPANE RING-CLEAVED PURINE DERIVATIVE BY HYDROGENATING PURINE DERIVATIVE HAVING CYCLOPROPANE RING | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2002-01-29 | — | — | US | disclosed |
| US-6156892-A | Purine derivatives having cyclopropane ring | SUMIKA FIRE CHEMICALS CO., LTD. (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0916674-A1 | Purine derivatives having cyclopropane ring | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |