Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.83 |
| ▸ | CTSL | P07711 | 14/20 | 0.83 |
| ▸ | CTSS | P25774 | 12/20 | 0.80 |
| ▸ | CTSB | P07858 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441698 | 0.89 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7450480 | 0.87 | CTSK (0.64) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7442705 | 0.86 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7451164 | 0.86 | CTSK (0.59) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7452830 | 0.85 | CTSL (0.78) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7444598 | 0.85 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7160147 | 0.84 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL8086234 | 0.83 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7322234 | 0.82 | CTSK (0.75) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7442711 | 0.82 | CTSL (0.75) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904284-B1 | 6-substituted amino-4-oxa-1-azabicyclo[3.2.0]heptan-7-one derivatives as cysteine protease inhibitors | NAEJA PHARMACEUTICAL INC (CA) | 2002-01-30 | — | — | EP | disclosed |
| US-5905076-A | TREATMENT OF MUSCULAR DYSTROPHY, ARTHRITIS, MYOCARDIAL INFARCTION, ALZHEIMER'S DISEASE, BACTERIAL INFECTION, COMMON COLD, OSTEOPOROSIS OR CANCER METASTASIS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 1999-05-18 | — | — | US | disclosed |
| EP-0904284-A1 | 6-SUBSTITUTED AMINO-4-OXA-1-AZABICYCLO (3,2,0) HEPTAN-7-ONE DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS | SYNPHAR LABORATORIES INC. (CA) | 1999-03-31 | — | — | EP | disclosed |
| WO-1997038008-A1 | 6-SUBSTITUTED AMINO-4-OXA-1-AZABICYCLO[3,2,0] HEPTAN-7-ONE DERIV ATIVES AS CYSTEINE PROTEASE INHIBITORS | SYNPHAR LABORATORIES INC. (US) | 1997-10-16 | — | — | WO | disclosed |