Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 13/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 2/20 | 0.34 |
| ▸ | PLAT | P00750 | 2/20 | 0.34 |
| ▸ | PROC | P04070 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452877 | 0.87 | HDAC1 (0.35) | HDAC1HDAC8HDAC6F10F2 | |
| SCHEMBL7220633 | 0.86 | F10 (0.42) | HDAC1HDAC8HDAC6F10F2 | |
| Trifluoroacetic Acid SCHEMBL7214094 | 0.81 | F10 (0.40) | HDAC1HDAC8HDAC6F10F2 | |
| SCHEMBL7214254 | 0.81 | TSHR (0.32) | HDAC1ACEHCRTR2 | |
| SCHEMBL7214250 | 0.80 | ELANE (0.34) | HDAC1HCRTR2 | |
| SCHEMBL7454004 | 0.78 | F10 (0.43) | F10F2PLGPROC | |
| SCHEMBL7214087 | 0.72 | ACACB (0.42) | F10F2PLGPLATPROC | |
| SCHEMBL7937461 | 0.72 | HDAC1 (0.56) | HDAC1HDAC8HDAC6F10ACE | |
| SCHEMBL7937458 | 0.72 | HDAC1 (0.56) | HDAC1HDAC8HDAC6F10ACE | |
| SCHEMBL5604870 | 0.71 | ALDH1A1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944386-B1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | claimed |
| EP-0944386-B1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001039759-A2 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-06-07 | — | — | WO | disclosed |