SCHEMBL7453115

SCHEMBL7453115

CCCCCCC([C]=O)C1CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
EPHX1 P07099 8/20 0.38
EPHX2 P34913 2/20 0.38
NAAA Q02083 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7463334 1.00 TSHR (0.38) TSHREPHX1EPHX2NAAA
SCHEMBL7452808 1.00 TSHR (0.38) TSHREPHX1EPHX2NAAA
SCHEMBL7458659 1.00 TSHR (0.38) TSHREPHX1EPHX2NAAA
SCHEMBL7457424 1.00 TSHR (0.38) TSHREPHX1EPHX2NAAA
SCHEMBL7457530 1.00 TSHR (0.38) TSHREPHX1EPHX2NAAA
SCHEMBL7458138 0.98 SHBG (0.38) TSHREPHX1EPHX2NAAA
SCHEMBL6988843 0.93 SHBG (0.39) TSHREPHX1EPHX2NAAA
SCHEMBL3885335 0.91 GPR84 (0.39)
SCHEMBL1335896 0.85 SHBG (0.41) EPHX1
SCHEMBL3877778 0.83 METAP1 (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1167375-A1 ERYTHROMYCIN DERIVATIVES HOKURIKU SEIYAKU CO., LTD. (JP) 2002-01-02 EP disclosed