Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | AR | P10275 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17890843 | 0.83 | AR (0.59) | MEN1KMT2ATP53GAAMAPT | |
| SCHEMBL22542432 | 0.81 | LTA4H (0.59) | MEN1KMT2ATP53GAAMAPT | |
| SCHEMBL27960960 | 0.81 | F2 (0.78) | MEN1KMT2ATP53GAAMAPT | |
| SCHEMBL16416215 | 0.80 | AR (0.60) | MEN1KMT2ATP53GAAMAPT | |
| SCHEMBL4325474 | 0.80 | MEN1 (0.67) | MEN1KMT2AGAAMAPTLTA4H | |
| Hydrochloric Acid SCHEMBL9131179 | 0.80 | F2 (0.76) | MEN1KMT2ATP53GAAMAPT | |
| SCHEMBL6376293 | 0.79 | AR (0.62) | MEN1KMT2ATP53GAAMAPT | |
| SCHEMBL1548538 | 0.78 | ALDH1A1 (0.56) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28494253 | 0.78 | AR (0.60) | MEN1KMT2ATP53GAAMAPT | |
| SCHEMBL7468581 | 0.78 | LTA4H (0.58) | MEN1KMT2ATP53GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977743-A1 | PROTEASE INHIBITORS | Smithkline Beecham (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998049152-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |