Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7506836 | 1.00 | CREBBP (0.46) | CREBBPBRD4TSHRHPGDALDH1A1 | |
| SCHEMBL7506825 | 1.00 | CREBBP (0.46) | CREBBPBRD4TSHRHPGDALDH1A1 | |
| SCHEMBL7453292 | 1.00 | CREBBP (0.46) | CREBBPBRD4TSHRHPGDALDH1A1 | |
| SCHEMBL7453297 | 1.00 | CREBBP (0.46) | CREBBPBRD4TSHRHPGDALDH1A1 | |
| SCHEMBL7453288 | 0.81 | USP2 (0.41) | CREBBPBRD4TSHRALDH1A1TP53 | |
| SCHEMBL7449138 | 0.80 | KMT2A (0.43) | HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL7512566 | 0.80 | KMT2A (0.43) | HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL9744632 | 0.80 | KMT2A (0.43) | HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL9745679 | 0.80 | KMT2A (0.43) | HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL6866934 | 0.79 | TSHR (0.55) | CREBBPBRD4TSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140821-A1 | LACTAMS | ISIS INNOVATION LIMITED (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035871-A1 | LACTAMS | ISIS INNOVATION LIMITED (GB) | 2000-06-22 | — | — | WO | disclosed |