Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457321 | 0.88 | DRD2 (0.49) | DRD2DRD4DRD3 | |
| SCHEMBL7474193 | 0.85 | DRD2 (0.67) | DRD2DRD4DRD3 | |
| SCHEMBL14507275 | 0.84 | — | — | |
| SCHEMBL7454517 | 0.81 | — | — | |
| SCHEMBL7477939 | 0.81 | DRD2 (0.59) | DRD2DRD4DRD3 | |
| SCHEMBL7473321 | 0.80 | DRD2 (0.52) | DRD2DRD4DRD3 | |
| SCHEMBL7474506 | 0.79 | DRD2 (0.59) | DRD2DRD4DRD3 | |
| SCHEMBL7462855 | 0.76 | HTR1A (0.34) | DRD2DRD4DRD3 | |
| SCHEMBL7474344 | 0.75 | DRD2 (0.56) | DRD2DRD4DRD3 | |
| SCHEMBL7476726 | 0.75 | DRD2 (0.56) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923576-B1 | 4-AMINOETHOXY-INDOLONE DERIVATIVES AS DOPAMINE D2 AGONISTS | WYETH CORP (US) | 2002-11-06 | — | — | EP | claimed |
| EP-0923576-B1 | 4-AMINOETHOXY-INDOLONE DERIVATIVES AS DOPAMINE D2 AGONISTS | WYETH CORP (US) | 2002-11-06 | — | — | EP | disclosed |