Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 1/20 | 0.48 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453081 | 0.91 | SLC5A1 (0.51) | SLC5A1SLC5A2KCNMA1TP53ALOX12 | |
| SCHEMBL7454361 | 0.84 | TP53 (0.52) | SLC5A1SLC5A2TP53ALOX12GABRG2 | |
| SCHEMBL7458627 | 0.83 | SLC5A1 (0.41) | SLC5A1SLC5A2KCNMA1LMNATP53 | |
| SCHEMBL7453223 | 0.80 | GABRG2 (0.45) | SLC5A1SLC5A2LMNATP53ALOX12 | |
| SCHEMBL7458456 | 0.80 | LMNA (0.45) | SLC5A1SLC5A2LMNAGABRG2GABRB3 | |
| SCHEMBL7449917 | 0.79 | GRM5 (0.57) | SLC5A1SLC5A2KCNMA1LMNATP53 | |
| SCHEMBL7454858 | 0.76 | SLC5A1 (0.51) | SLC5A1SLC5A2KCNMA1TP53ALOX12 | |
| SCHEMBL18329289 | 0.76 | SLC5A1 (0.46) | SLC5A1SLC5A2KCNMA1TP53ALOX12 | |
| SCHEMBL7453711 | 0.76 | GRM5 (0.58) | LMNANPSR1KMT2ASMN1; SMN2HSD17B3 | |
| SCHEMBL12066859 | 0.76 | MAPK1 (0.52) | LMNATP53NPSR1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151361-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151361-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-12-08 | — | — | WO | disclosed |