Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.45 |
| ▸ | WNT3A | P56704 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11621763 | 0.88 | P2RX7 (0.56) | P2RX7CTNNB1WNT3ALMNASMN1; SMN2 | |
| SCHEMBL4970018 | 0.84 | P2RX7 (0.59) | P2RX7CTNNB1WNT3ALMNASMN1; SMN2 | |
| SCHEMBL27890805 | 0.84 | FAAH (0.52) | P2RX7FAAHALDH1A1MAPTDAGLA | |
| Hydrochloric Acid SCHEMBL7996665 | 0.83 | P2RX7 (0.57) | P2RX7CTNNB1WNT3ALMNASMN1; SMN2 | |
| SCHEMBL20795421 | 0.80 | GAA (0.43) | P2RX7CTNNB1WNT3ALMNASMN1; SMN2 | |
| SCHEMBL2632669 | 0.79 | P2RX7 (0.61) | P2RX7CTNNB1WNT3ALMNASMN1; SMN2 | |
| SCHEMBL11243043 | 0.78 | P2RX7 (0.51) | P2RX7CTNNB1WNT3ASMN1; SMN2KDM4E | |
| SCHEMBL11709541 | 0.77 | CTNNB1 (0.57) | CTNNB1WNT3AL3MBTL1HPGD | |
| SCHEMBL2231066 | 0.77 | P2RX7 (0.59) | P2RX7CTNNB1WNT3ALMNASMN1; SMN2 | |
| SCHEMBL6077799 | 0.77 | P2RX7 (0.64) | P2RX7CTNNB1WNT3ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000003712-A1 | 1-4-DIHYDROPYRIDINES WITH PYRIDINYL GROUP AS CALCIUM BLOCKERS | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |