Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449284 | 0.79 | SLC6A3 (0.48) | SLC6A3SLC6A2SLC6A4KCNA5KCNE1 | |
| SCHEMBL1753813 | 0.78 | SLC6A3 (0.52) | SLC6A3SLC6A2SLC6A4KCNA5KCNE1 | |
| SCHEMBL18513573 | 0.78 | SLC6A3 (0.52) | SLC6A3SLC6A2SLC6A4KCNA5KCNE1 | |
| SCHEMBL14768852 | 0.78 | SLC6A3 (0.52) | SLC6A3SLC6A2SLC6A4KCNA5KCNE1 | |
| SCHEMBL29543279 | 0.78 | SLC6A3 (0.52) | SLC6A3SLC6A2SLC6A4KCNA5KCNE1 | |
| SCHEMBL18513572 | 0.76 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4KCNA5KCNE1 | |
| SCHEMBL7366925 | 0.76 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4KCNA5KCNE1 | |
| SCHEMBL5014425 | 0.76 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4KCNA5KCNE1 | |
| SCHEMBL7355983 | 0.76 | CYP3A4 (0.50) | SLC6A3SLC6A2SLC6A4KCNA5KCNE1 | |
| SCHEMBL12125671 | 0.76 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4KCNA5KCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025090-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2000-11-08 | — | — | EP | disclosed |
| EP-1025090-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999015508-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-04-01 | — | — | WO | disclosed |